Hormones play a powerful and coordinated role in the process of labour, each contributing to a complex, carefully orchestrated process. From initiating contractions (or surges) to creating bonds between mother and baby, these hormones—oxytocin, oestrogen, progesterone, beta-endorphins, adrenaline, cortisol, and prolactin—are essential to a successful and positive birth experience. Here, we explore each hormone’s unique role in labour, its functions, and how they work in harmony to bring new life into the world.